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  • RESEARCH

    Understanding how the structure of blood clots affects thrombosis risk

    University of Leeds | Professor Robert Ariens

    Thrombosis occurs when a clot forms in a blood vessels and prevents the blood supply from reaching the tissues supplied by that vessel. Clots are primarily made up of platelets embedded in a network of fibres made of a protein called fibrin...

  • RESEARCH

    How do immune cells help to protect against atherosclerosis?

    University of Cambridge | Professor Ziad Mallat

    BHF Professor Ziad Mallat at the University of Cambridge is studying how immune cells called type 2 innate lymphoid (or ILC2) cells, could help to protect against atherosclerosis, when arteries become furred up and narrow with fatty plaques...

  • RESEARCH

    A tug of war to help new blood vessels grow

    University of East Anglia | Dr Stephen Robinson

    Dr Stephen Robinson studies how cells that form the inner lining of blood vessels, endothelial cells, interact with their environment. This process may affect how they are involved in angiogenesis, the growth of new blood vessels. Angiog...

  • RESEARCH

    Understanding how zinc controls blood clotting

    Anglia Ruskin University | Dr Nicholas Pugh

    Blood clots form when small cells in the blood called platelets are activated and stick together. Controlling when platelets become activated is essential to ensure clotting happens when it is needed - for example, after injury - whilst lim...

  • RESEARCH

    Sirolimus: A complementary antiplatelet drug?

    University of Bristol | Professor Ingeborg Hers

    Whenever we get a cut or a wound, platelets come together to form a clot and stop the continued bleeding. However, sometimes clots can cause blockages inside the blood vessels, which can eventually cause a heart attack or a stroke. To preve...

  • RESEARCH

    How do platelet surface receptors ‘ITAM’ regulate function in health and disease?

    University of Birmingham | Professor Stephen P Watson

    BHF Professor Stephen Watson from the University of Birmingham has been awarded a five year grant totalling almost £1.5million to look at the effects of tiny cells called platelets in our circulation. We know that platelets ‘plug’ a site of...

  • RESEARCH

    Spontaneous coronary artery dissection - understanding the causes

    University of Leicester | Dr David Adlam

    Although spontaneous coronary artery dissection (SCAD) is rare, it can have the devastating consequence of a heart attack. Research into this condition is very important because traditionally it has not received a lot of attention in the UK...

  • RESEARCH

    Targeting connexins to control blood clotting

    University of Reading | Professor Jonathan Gibbins

    Platelets are tiny blood cells that contribute to a blood clot following injury. Thrombosis is where over active platelets form a blood clot inside a blood vessel. Such clots can block blood supply to the heart or brain and lead to a heart...

  • RESEARCH

    Studying pulmonary hypertension in a leading international research centre

    University of Sheffield | Dr Alfred Thompson

    Dr Alfred Thompson has been awarded a prestigious Fulbright-BHF Scholar Award to spend one year working in Professor Marlene Rabinovitch’s world-leading pulmonary hypertension laboratory at Stanford University. Dr Thompson studies pulmonary...

  • RESEARCH

    Why blood vessels can become like bone in old age

    King's College London | Professor Catherine Shanahan

    As we age, the smooth muscle cells that make up our blood vessels can start to calcify, becoming rigid like bone. The technical term for this phenomenon is vascular calcification. It can cause high blood pressure, heart attacks or strokes a...