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  • RESEARCH

    Using stem cells to study atherosclerosis and Marfan syndrome

    University of Cambridge | Dr Sanjay Sinha

    Smooth muscle cells (SMCs) in the blood vessel wall contribute to the ‘furring up’ of vessels in coronary heart disease and stroke. SMCs are also involved in an inherited condition known as Marfan syndrome, where a defect in fibrillin-1, a ...

  • RESEARCH

    How can we encourage men to use physical activity interventions?

    University of Bristol | Professor Russell Jago

    We know that physical exercise helps to reduce the risk of heart and circulatory disease in both adults and children, by helping to control risk factors for the disease – weight, blood pressure and cholesterol. However, despite these health...

  • Angiotensin receptor blockers (ARBs)

    Everything you need to know about ARBs. Read what they are, how they work, their possible side effects and more.

  • RESEARCH

    Studying a protein that helps new blood vessels grow

    University College London | Dr Claudio Raimondi

    Finding out how new blood vessels grow is important for developing treatments to restore blood flow in tissues that are starved of oxygen (ischaemic tissue). Neuropilin-1 (NRP1) is a protein in the endothelial cells that line the inside of...

  • RESEARCH

    Understanding the roles of the regulatory enzymes DDAH in the brain’s circulation

    University of Glasgow | Dr Alyson Miller

    This team is addressing a gap in knowledge about blood vessel health in the brain, hoping to identify new ways to tackle diseases such as stroke. The health and function of our blood vessels is highly influenced by the layer of cells linin...

  • Volunteering FAQs

    If you're thinking about volunteering with us, you may have some questions. Here are the answers to our most frequently asked questions about volunteering.

  • RESEARCH

    Studying the zebrafish to find new ways to protect against plaques in vessels

    University of Sheffield | Professor Paul Evans

    Atherosclerosis, the build-up of fatty deposits in blood vessels, begins at the branches and bends of arteries. This plaque disturbs blood flow, causing a phenomenon called low ‘wall shear stress’ (WSS). In turn, this leads to abnormal grow...

  • Quiz: How much do you know about nuts?

    Nuts are a healthy and nutritious snack. But how much do you know about them?

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  • RESEARCH

    Does a molecule called pentraxin-3 reduce brain inflammation after a stroke?

    University of Manchester | Dr Emmanuel Pinteaux

    During a stroke the blood supply to part of the brain is cut off, causing brain cells to become damaged or die. Inflammation – activation of the immune system - is an important defence mechanism that the body uses during injury or infection...