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  • RESEARCH

    Understanding how calcium-sensing receptors influence blood pressure

    St George's, University of London | Professor Anthony Albert

    Abnormal contraction of blood vessels leads to high blood pressure, which in turn is a significant risk factor for heart and circulatory diseases. Recently, a group of molecules called calcium-sensing receptors (CaSRs) have been shown to ...

  • RESEARCH

    How proteins cluster to ensure a regular heartbeat

    University of Cambridge | Dr Antony Jackson

    On the surface of each heart muscle cell are tiny pores, or ion channels. These open and close to let sodium, calcium and potassium ions flow in and out of the cells, and generate the electrical signal that causes the heart to contract and ...

  • RESEARCH

    Uncovering the mechanisms behind pulmonary arterial hypertension, towards a cure

    University of Sheffield | Professor Allan Lawrie

    Pulmonary arterial hypertension (PAH) is a rare but fatal disease. It is most common in young women, who – if untreated – have a prognosis worse than some cancers. PAH is driven by unchecked cell growth in the blood vessels in the lung. Thi...

  • RESEARCH

    How do prostanoids work to treat pulmonary hypertension?

    University of Bradford | Professor Timothy Palmer

    Supervised by Professor Timothy Palmer, a PhD student is working out how a class of drugs called prostanoids could help people with pulmonary arterial hypertension, or PAH, live longer. PAH is a disease where lung artery walls become progr...

  • RESEARCH

    Preventing brain inflammation during a stroke

    University of Manchester | Dr Emmanuel Pinteaux

    Dr Emmanuel Pinteaux from the University of Manchester is searching for ways to prevent inflammation in the brain’s blood vessels during a stroke. Whilst inflammation is an important defence against injury or infection, in the brain it can ...

  • RESEARCH

    Developing a new ‘virtual platelet’ to study blood clotting

    University of Reading | Professor Jonathan Gibbins

    Professor Jonathan Gibbins and his colleagues at the University of Reading are using a virtual model of a platelet to study blood clotting and look for new anti-clotting medicines to prevent people from having a heart attack or stroke. Pla...

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  • RESEARCH

    The factors involved in forming blood clots

    Anglia Ruskin University | Dr Nicholas Pugh

    Understanding how platelets stick together may reveal a new way to prevent blood clotting that could ultimately prevent heart attacks or strokes. When blood clots form in blood vessels they can block the flow of blood and can cause heart...

  • RESEARCH

    Do platelets cause inflammation in people with diabetes?

    University of Leeds | Professor Khalid Naseem

    Diabetes is a complex disorder characterized by too much sugar (glucose) in the blood. People with diabetes are at high risk of developing heart and circulatory disease, partly because of inflammation which damages blood vessels. Unders...