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  • RESEARCH

    Understanding how neuropeptide-Y affects the heart

    University of Oxford | Professor Neil Herring

    The speed and strength of the heartbeat can be increased by a group of nerves that work by releasing a chemical called norepinephrine, a neurotransmitter. Whilst norepinephrine is useful in healthy individuals during exercise, it can trigge...

  • Heart research breakthroughs under threat from funding shortfall

    We're calling on Government to commit to increased funding for cardiovascular research to safeguard the future of UK research, as our new analysis shows that cardiovascular disease research funding faces a shortfall of more than a quarter of a billion pounds between 2025 and 2035.

  • RESEARCH

    Harnessing the immune system to protect against heart failure

    Imperial College London | Dr Susanne Sattler

    After a heart attack, damage to the heart muscle can lead to heart failure. This is when the heart lacks the strength to pump blood around the body efficiently. Current treatments for heart failure are limited, and researchers around the wo...

  • £630k research project to determine best treatment after a heart attack

    Nearly 20,000 people in Scotland will be included in a clinical trial to determine the best clot busting drug treatment for people after they have suffered a heart attack.

  • RESEARCH

    Understanding how the enzyme NOX4 protects against heart failure

    King's College London | Professor Ajay Shah

    Researchers at the King’s College London BHF Centre of Research Excellence, led by BHF Professor Ajay Shah have been studying enzymes called NADPH oxidases (NOXs). These enzymes make chemicals – called free radicals – which are considered b...

  • RESEARCH

    Understanding how amyloid forms in the heart

    University of Liverpool | Dr Jillian Madine

    Amyloid is a substance made up of a mixture of proteins that have folded abnormally and solidified together. Amyloid can build up in tissues and organs such as the heart and the aorta. Cardiovascular amyloid is most common in people over th...

  • RESEARCH

    The brain-heart connection in health and disease

    University College London | Professor Alexander Gourine

    BHF-funded researchers at University College London are studying the connection between our brain and heart, and how activity through this connection declines in heart disease. Specialised nerves connect our brain to our heart. These nerve...

  • RESEARCH

    Revealing the proteins that protect the heart

    University College London | Professor Derek Yellon

    Professor Derek Yellon and his colleagues at University College London (UCL) are working out which proteins can protect the heart from damage when blood supply is restored to the heart muscle after a heart attack. Damage caused by the delay...

  • RESEARCH

    How does COPD increase the risk of heart failure?

    University of Manchester | Dr Christopher Miller

    Chronic obstructive pulmonary disease (COPD) is the name for a group of conditions that cause severe breathing difficulties. A third of people with COPD also have heart failure. You might expect this to be because the two diseases share ris...

  • RESEARCH

    Testing a new drug to treat broken heart syndrome

    University of Aberdeen | Professor Dana Dawson

    Supervised by Dr Dana Dawson, this PhD student is investigating a new way to treat a disorder called acute stress-induced (Takotsubo) cardiomyopathy, also known as ‘broken heart’ disease. In broken heart syndrome, stressful situations t...