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  • RESEARCH

    Studying a master switch that underlies heart hypertrophy

    University College London | Dr Vishwanie Budhram-Mahadeo

    The heart’s specialised muscle cells, called cardiomyocytes, help pump blood around the body. Stress or damage can force the heart to work harder, which causes the cells to adapt to the workload by growing larger, a process called hypertrop...

  • RESEARCH

    Predicting the risk of taking NSAIDs on the heart

    Imperial College London | Professor Jane A Mitchell

    Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are good at treating inflammation but may also increase a person’s chance of having a heart attack or stroke. However, exactly how they increase this risk is uncertain. NSAID...

  • RESEARCH

    Could heart fibroblast cells help to repair damage?

    Imperial College London | Professor Prakash P Punjabi

    Supervised by Prakash Punjabi, a Clinical Research Training Fellow is studying cells within the heart called fibroblasts and how they can support the growth of new heart tissue. Fibroblasts help the body to repair itself after injury. But ...

  • RESEARCH

    Understanding heart metabolism in diabetes and aortic stenosis

    University of Leeds | Dr Eylem Levelt

    People with aortic stenosis (a narrowing of the aortic valve opening) often also have type 2 diabetes. Having diabetes can affect how well people recover from having their aortic valve replaced, but it is not known why. The heart is hard...

  • Penny Lancaster surprises children with heart conditions

    Penny Lancaster visits the Royal Brompton Hospital to support the British Heart Foundation’s Christmas campaign to fund research to keep more families together

  • RESEARCH

    Can exercise cause heart muscle changes that resemble cardiomyopathy?

    St George's, University of London | Professor Sanjay Sharma

    Supervised by Professor Sanjay Sharma, this Clinical Research Training Fellowship is focusing on finding out whether intense physical activity can cause heart muscle remodelling that resembles a rare heart muscle disease called Left Ventric...

  • Video: A life with spiders and a heart condition

    Read how a heart rhythm problem hasn't stopped Carl Portman's jungle adventures, and watch a video of Carl with his spiders and talking about his ICD.

  • RESEARCH

    Do Popeye proteins lead to heart disease?

    Imperial College London | Professor Dr Thomas Brand

    Popeye domain containing (Popdc) proteins, named after the cartoon character, are highly expressed in the heart and muscles. Mutations in Popdc genes have been associated with heart rhythm disorders and muscular dystrophy. Professor Tho...

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  • RESEARCH

    3D imaging to detect abnormal heart muscle thickening

    University College London | Dr Charlotte Manisty

    Supervised by Dr Charlotte Manisty, this Clinical Research Training Fellow is working out why some people develop excessively thick heart muscle in response to stress, putting them at risk of heart failure. When subjected to stresses, fo...