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There are 3448 result(s) for coronary disease mortality
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RESEARCH
How do potentially deadly aneurysms grow?University of Leicester | Professor Matthew Bown
<p>An abdominal aortic aneurysm (AAA) is a balloon-like swelling of the aorta, the body’s main blood vessel. If AAAs become large and burst, they can cause internal bleeding and sudden death. Surgery to repair AAA is risky, but doctor...
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RESEARCH
Understanding the causes of short QT syndromeUniversity of Manchester | Professor Henggui Zhang
BHF has awarded a 3-year PhD studentship totalling around £100,000 to take place in the Biological Physics Group at the School of Physics and Astronomy, University of Manchester under the supervision of Professor Henggui Zhang and Professor...
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RESEARCH
How SUMO wrestles heart injury after a heart attackUniversity of Bristol | Professor Jeremy Henley
Dr Jeremy Henley and colleagues at the University of Bristol have been awarded a grant to investigate how a protein called SUMO can help protect the heart from injury. The SUMO protein is attached to a specific protein in mitochondria, whic...
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RESEARCH
Can we better predict sudden cardiac death risk from an ECG?University College London | Professor Pier Lambiase
Internal cardiac defibrillators can prevent dangerous heart rhythms by delivering a shock to the heart to restart normal pacing. However, it is difficult to accurately predict which patients will develop a lethal heart rhythm and should rec...
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RESEARCH
Activating NKT cells to stop the immune system rejecting a heart transplantUniversity of Birmingham | Dr Nicholas Jones
Heart transplantation may be the only option available for some patients with irreversibly damaged and failing hearts. But the donor heart can be rejected by the person’s immune system. Although certain types of immune cells are responsible...
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RESEARCH
How chemically modifying proteins could control blood clottingUniversity of Reading | Professor Jonathan Gibbins
Professor Jonathan Gibbins is studying how tiny blood cells called platelets involved in blood clotting are controlled. Platelets prevent the body from losing blood after injury by forming blood clots. While this is vital for survival, ...
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RESEARCH
Can molecules called chemokines flag heart transplant rejection?Newcastle University | Professor Simi Ali
Supervised by Dr Simi Ali, the PhD student funded by this grant is investigating ways to help prevent rejection of donor hearts. Heart transplantation is often the only option for patients with end-stage heart failure. Better drugs mean t...
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RESEARCH
How GLP-1 producing cells in the brain affect the heart and circulatory systemUniversity College London | Professor Stefan Trapp
Glucagon-like-peptide-1 (GLP-1) is a molecule made by the gut and the brain that reduces appetite and helps control blood sugar levels. Drugs that mimic the effects of GLP-1 are currently used to lower body weight and treat diabetes. Howeve...
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RESEARCH
What controls platelet secretion in blood clotting?University of Sheffield | Professor Martina E Daly
When blood vessels are injured, cells called platelets gather at the site of injury, forming a clot to stop excessive bleeding. At the injury site, platelets release a mixture of proteins and small molecules that activate more platelets – a...
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RESEARCH
How tissue factor triggers blood clottingCardiff University | Professor Peter Collins
When blood clots form in blood vessels they block the flow of blood and can cause heart attacks and strokes. Finding new ways to manage blood clotting could prevent and treat blood clots that lead to a heart attack or stroke. Blood clot...