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There are 3741 result(s) for coronary disease mortality
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RESEARCH
Developing urgently needed treatments for aortic aneurysmsUniversity of Leeds | Dr Marc Bailey
An abdominal aortic aneurysm (AAA) is a ballooning of the main blood vessel in the abdomen. Once an aneurysm develops it tends to grow over time with no symptoms, and if it bursts, it is usually fatal. The only treatment is surgery, but thi...
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RESEARCH
Developing ways to personalise digoxin treatmentUniversity of Birmingham | Dr Davor Pavlovic
Digoxin is a common treatment for people with atrial fibrillation and heart failure, but it doesn’t always work as well as expected. Dr Pavlovic’s team at the University of Birmingham has previously shown that substances in the blood called...
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RESEARCH
Safe guarding the cell’s energy sources to protect the heart during a heart attackUniversity College London | Professor Derek Hausenloy
Ischaemic heart disease commonly presents as a heart attack due to a blockage in one of the main heart arteries, depriving the heart muscle of oxygen and nutrients resulting in heart muscle injury. New treatments are required to protect the...
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RESEARCH
Understanding how the enzyme NOX4 protects against heart failureKing's College London | Professor Ajay Shah
Researchers at the King’s College London BHF Centre of Research Excellence, led by BHF Professor Ajay Shah have been studying enzymes called NADPH oxidases (NOXs). These enzymes make chemicals – called free radicals – which are considered b...
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RESEARCH
Studying flecainide to develop safer drugs for arrhythmiaUniversity of Leeds | Professor Derek S Steele
In a recent breakthrough, scientists have discovered that the drug, flecainide, is an effective treatment for a type of inherited heart rhythm disturbance (arrhythmia) linked to sudden cardiac death, called catecholaminergic polymorphic tac...
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RESEARCH
Investigating heart proteins that respond to stressUniversity of Reading | Professor Angela Clerk
Professor Angela Clerk is studying how certain signals that help the heart respond to stress are regulated in the heart. When the heart goes through a stressful event, such as high blood pressure or a heart attack, heart muscle cells die...
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RESEARCH
In the mind: the brain and blood pressure controlUniversity of Bristol | Professor Julian Paton
Millions of people in the UK are diagnosed with high blood pressure (hypertension) which significantly increases a person’s risk of developing heart disease. Medicines are available to treat it but can be ineffective in up to half of patien...
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RESEARCH
Developing a better blood test to diagnose heart attacksKing's College London | Professor Michael Marber
Only about ten per cent of people in accident and emergency departments with chest pain will be having a heart attack. Professor Michael Marber is trying to find better ways to diagnose them. Currently, doctors identify heart attack pati...
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RESEARCH
Improving risk assessments for people with inherited heart conditionsImperial College London | Dr Fu Siong Ng
Dr Fu Siong Ng is studying why some people with an inherited heart condition are at greater risk of dying suddenly than others. Despite advances in genetic research, it is a challenge for doctors to predict which people with inherited h...
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RESEARCH
Deciphering the intricate process controlling plateletsUniversity of Birmingham | Dr Alexandra Mazharian
BHF Intermediate Basic Science Research Fellow Dr Alexandra Mazharian is working out the intricate processes behind production of platelets - small fragments of bone marrow cells called megakaryocytes (MK cells) that circulate in the blood ...