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There are 3433 result(s) for coronary disease mortality
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RESEARCH
Developing urgently needed treatments for aortic aneurysmsUniversity of Leeds | Dr Marc Bailey
An abdominal aortic aneurysm (AAA) is a ballooning of the main blood vessel in the abdomen. Once an aneurysm develops it tends to grow over time with no symptoms, and if it bursts, it is usually fatal. The only treatment is surgery, but thi...
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RESEARCH
Studying proteins that prevent blood clottingImperial College London | Professor David A Lane
Blood clotting is a vital part of the healing process after injury. But if blood clots form in blood vessels they can block the flow of blood and cause diseases such as heart attacks or strokes. Finding new ways to prevent blood clotting co...
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RESEARCH
How Kv7 ion channels contribute to relaxation in blood vessels and what changes in hypertensionSt George's, University of London | Professor Iain Greenwood
Adults with high blood pressure have a higher risk of developing heart and circulatory disease. High blood pressure can arise as a result of blood vessels losing their elasticity, meaning that blood vessels cannot expand and contract as eff...
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RESEARCH
Looking for treatments for essential thrombocythaemiaUniversity of Cambridge | Dr Cedric Ghevaert
People with the condition essential thrombocythaemia (ET) have too many platelets in the blood and are at increased risk of cardiovascular events. This is because an excess of platelets can lead to excessive clotting and blockage of the ve...
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RESEARCH
Do RIP proteins control life and death in heart muscle cells?University of Reading | Professor Angela Clerk
Professor Angela Clerk is studying how heart muscle cells die after a heart attack to identify points where we could intervene and prevent it. The team is studying a new form of cell death called necroptosis, which could be important in the...
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RESEARCH
Investigating a new suspect in hypertensionSt George's, University of London | Professor Anthony Albert
Nearly 30 per cent of adults in the UK have high blood pressure, which raises the risk of heart disease threefold. Despite how common it is, today’s medicines can fail to tightly control blood pressure in many people. This team in London ar...
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RESEARCH
Targeting heart muscle motors to treat heart failureKing's College London | Dr Thomas Kampourakis
In the search for new heart failure treatments, scientists have been studying the tiny muscle motors of heart cells that cause them to relax and contract. These motors are made up of two types of miniscule filaments – thick and thin – that ...
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RESEARCH
Pinpointing the links between air pollution and heart damageUniversity of Manchester | Dr Holly Shiels
Short exposures to air pollution can trigger heart attacks, strokes and irregular heart rhythms, especially in people already at risk of these conditions. Evidence suggests a link between a group of air pollutants called polycyclic aromatic...
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RESEARCH
Understanding how platelets are switched on to help improve anti-clotting treatmentsUniversity of Bristol | Professor Stuart Mundell
Heart attacks occur when blood flow is blocked, usually by a blood clot developing in the blood vessels of the heart. Platelets are the major cells involved in the formation of blood clots and can be ‘switched on’ by substances inside the b...
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RESEARCH
Targeting ZONAB to better understand inflammation and blood vessel formationUniversity College London | Professor Dr Maria Balda
The insides of blood vessels are made up of a thin sheet of cells, called endothelial cells, which form a barrier between the passing blood and the vessel wall. Endothelial cells have many functions, from responding to stimuli within the bl...