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There are 3435 result(s) for coronary disease mortality
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RESEARCH
Studying storage granules to understand bleeding disordersUniversity College London | Professor Daniel F Cutler
Endothelial cells that line the blood vessel contain cigar shaped storage granules called Weibel-Palade Bodies (WPBs), which release factors involved in blood clotting and inflammation. WPBs are malformed and do not function properly in Vo...
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RESEARCH
Why do women with heart failure have a better prognosis than men?Imperial College London | Professor Kenneth MacLeod
Dr Kenneth MacLeod and his team at Imperial College London are investigating why high blood pressure causes heart failure in more women than men, yet more women survive. Heart failure is a serious condition where the heart cannot pump b...
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RESEARCH
A tug of war to help new blood vessels growUniversity of East Anglia | Dr Stephen Robinson
Dr Stephen Robinson studies how cells that form the inner lining of blood vessels, endothelial cells, interact with their environment. This process may affect how they are involved in angiogenesis, the growth of new blood vessels. Angiog...
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RESEARCH
Shedding light on the cause of a dangerous condition that can develop in unborn babiesSt George's, University of London | Dr Pia Ostergaard
Foetal hydrops is a rare but very serious condition in which an unborn baby accumulates excessive fluid within their body. Six out of ten babies with foetal hydrops die, and those that survive often have very severe complications. There are...
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RESEARCH
Targeting a clot protein to prevent heart attacksUniversity of Leeds | Dr Richard J Pease
Blood clots prevent excess bleeding from cuts to the skin, but they can also be dangerous. For example, heart attacks, many strokes, and deep vein thrombosis all occur when clots form inside a blood vessel in the body. The main component ...
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RESEARCH
Studying the zebrafish to find new ways to protect against plaques in vesselsUniversity of Sheffield | Professor Paul Evans
Atherosclerosis, the build-up of fatty deposits in blood vessels, begins at the branches and bends of arteries. This plaque disturbs blood flow, causing a phenomenon called low ‘wall shear stress’ (WSS). In turn, this leads to abnormal grow...
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RESEARCH
Cutting edge technology for drug discovery and biology researchUniversity of Nottingham | Professor Jonas Emsley
The BHF is helping researchers at the University of Nottingham lead the way in drug discovery by contributing £235,111 towards a new state-of-the-art advanced chemical and biomolecular characterisation facility in the Nottingham Centre for ...
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RESEARCH
The role of the immune system in cardiac transplantationKing's College London | Professor Graham Lord
Pioneering research has led to advances in preventing organ rejection soon after a heart transplant. Transplant patients receive treatment to modify their immune systems – maximising the chances of their body accepting the donor heart. Howe...