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There are 3741 result(s) for coronary disease mortality
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RESEARCH
On the quest for treatments for dangerous aortic aneurysms in Marfan syndromeUniversity of Cambridge | Dr Sanjay Sinha
Marfan syndrome is an inherited condition that causes problems with the body’s connective tissue. It is caused by faults in a particular gene, and is therefore passed down through families. The most severe consequence of Marfan syndrome is ...
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RESEARCH
What dictates where plaques form in the blood vessels?University of Oxford | Dr Ellie Tzima
Dr Ellie Tzima and colleagues at the University of Oxford are working out how plaques form in atherosclerosis - an inflammatory disease where fatty plaques gradually build up on the inner surface of blood vessels. Over time, these plaques c...
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RESEARCH
Understanding the molecular changes that could lead to aortic aneurysmKing's College London | Professor Manuel Mayr
Aneurysms are balloon-like bulges that form in blood vessels, for example in the body's main artery in the chest - the aorta. Some aneurysms may stay small but others can burst and be fatal. There are currently no effective treatments for a...
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RESEARCH
Finding out how diabetes affects our blood vesselsUniversity of Oxford | Professor Kim A Dora
Professor Kim Dora and colleagues from the University of Oxford are interested in how positively charged calcium atoms, known as calcium ions, affect blood vessel narrowing. The level of calcium ions in cells lining the blood vessels co...
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RESEARCH
Sick sinus syndrome – lessons from endurance athletesUniversity of Manchester | Dr Gwilym Morris
Dr Gwilym Morris from the University of Manchester is to do a 2-year study looking at a condition called sick sinus syndrome (SSS). SSS affects the function of the heart’s natural internal pacemaker called the sinoatrial node. This node nor...
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RESEARCH
Studying BMP9, a potential therapy for pulmonary arterial hypertensionUniversity of Cambridge | Dr Wei Li
Pulmonary arterial hypertension (PAH) is a rare but devastating condition, for which effective treatments are urgently needed. In PAH, the blood pressure in the arteries supplying the lungs is very high. This puts a strain on the right side...
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RESEARCH
Creating the first detailed 3D maps of the heart’s electrical conduction systemUniversity of Manchester | Dr Halina Dobrzynski
Models of human anatomy have been used for centuries to teach doctors and improve our understanding of health and disease. In recent decades, the treatment of heart defects in babies has been vastly improved thanks to detailed anatomical mo...
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RESEARCH
Understanding why a hole in the heart increase risk of irregular heart rhythmsKing's College London | Professor Mark O Neill
Some babies are born with a hole in the wall between the two top chambers of their heart. This is known as an atrial septal defect (ASD). The hearts of people with ASDs often become stiffer through a process called fibrosis, which can lead ...
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RESEARCH
Pre-eclampsia – effect of certain growth factors on the mother’s blood vesselsUniversity of Nottingham | Professor David Bates
Pre-eclampsia in pregnancy, is one of the main causes of illness or death in pregnant women. Complications such as high blood pressure, swelling and the presence of protein in urine can commonly lead to life-threatening conditions such as l...
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RESEARCH
Can we repair damaged endothelial cells?King's College London | Dr Lingfang Zeng
Supervised by Dr Lingfang Zeng, a PhD student will work out how we can turn ‘master’ cells within blood vessel walls into lining cells, to repair damaged blood vessels. Endothelial cells lining the inner surface of blood vessels form a sin...