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There are 3435 result(s) for coronary disease mortality
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RESEARCH
Can stem cells help us restore blood flow to the limbs?University of Bristol | Professor Paolo Madeddu
Peripheral artery disease (PAD) is a common circulatory problem where arteries become narrowed, reducing blood flow to the limbs. Over a quarter of people with critical limb ischemia (CLI), the most advanced form of PAD, are unsuitable for ...
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RESEARCH
Microbubble contrast agents for improved ultrasound imaging of blood vesselsHeriot Watt University, Edinburgh | Dr Vassilis Sboros
Heart and circulatory disease is Britain’s biggest killer. New methods are urgently needed to quickly and accurately diagnose problems with the heart and circulatory system so that they can be treated or monitored before they become more se...
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RESEARCH
Structure-function mapping of the heart to understand abnormal heart rhythmsUniversity of Leicester | Professor G Andre Ng
Ventricular arrhythmias can lead to sudden cardiac death. There is currently no method of preventing sudden cardiac death, and there is a need to understand the underlying electrical and nervous disruption that causes the abnormal rhythm. T...
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RESEARCH
Understanding the early stages of how our veins and arteries stiffen with ageUniversity of East Anglia | Dr Derek Warren
As we age, our veins and arteries become less flexible, and this contributes to the development of heart and circulatory disease. The biological processes that initiate the stiffening of our blood vessels are still not well understood. By u...
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RESEARCH
Pumping out sodium to restore heart function in heart failureKing's College London | Professor Michael Shattock
To work normally, heart muscle cells need to turn precise electrical impulses from nerves into the contracting motion of the heartbeat. During the heartbeat, each muscle cell releases a minutely timed burst of charged molecules to instruct ...
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RESEARCH
Improving the lives of patients with tetralogy of FallotImperial College London | Professor Michael Gatzoulis
Tetralogy of Fallot affects approximately one in every 3,600 births. It is the most common cyanotic congenital heart defect present at birth (where the baby’s skin has a blue appearance because it is not receiving enough oxygen-carrying blo...
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RESEARCH
Does too much oesteopontin cause left ventricular hypertrophy?University of Glasgow | Dr Martin McBride
Dr Martin McBride and co-workers at the University of Glasgow are investigating the underlying causes of left ventricular hypertrophy, where there is enlargement of the muscle in the left bottom chamber of the heart. Left ventricular hypert...
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RESEARCH
Can BMP9 prevent septic shock?University of Cambridge | Dr Wei Li
Sepsis is a serious condition, caused by infection, which can lead to septic shock. Septic shock is when our own immune system overreacts, and it often has a damaging effect on the lungs, leading to acute respiratory distress syndrome (ARDS...
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RESEARCH
Trying to detect Acute Type A aortic dissection (AAD) before it’s too lateUniversity of Liverpool | Dr Riaz Akhtar
The aorta is the major artery of the human circulation. It has to withstand very high pressures to distribute blood from the heart all around the body. Acute Type A aortic dissection (AAD) is an uncommon but very serious condition in which ...
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RESEARCH
What triggers an aneurysm to get bigger, and can we stop it?University of Leeds | Dr Marc Bailey
Abdominal aortic aneurysm (AAA) is a ballooning of the main blood vessel in the body, the aorta. AAAs tend to grow over time and eventually may rupture, which can be fatal. At the moment, the only treatment is surgery if the aneurysm is lar...