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There are 3739 result(s) for coronary disease mortality
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RESEARCH
Investigating the potential of stem cells in the heartImperial College London | Professor Prakash P Punjabi
The BHF Clinical Research Training Fellowship is providing three years of funding totalling over £200,000 to consultant surgeon Mr Prakash Punjabi and a team at Imperial College. Together they will investigate the use of stem cells to treat...
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RESEARCH
How is the behaviour of cells lining blood vessels controlled?University of Cambridge | Dr Helle F Jorgensen
Supervised by Dr Helle Jorgensen, a PhD student is studying what influences vascular smooth muscle cell behaviour in disease. Vascular smooth muscle cells within the wall of blood vessels change their behaviour in disease in response to...
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RESEARCH
How do our genes influence the aorta, the body’s main blood vessel?Imperial College London | Professor Stuart Cook
Supervised by Professor Stuart Cook, a Clinical Research Training Fellow is working out which genes determine the stiffness and size of the main blood vessel exiting the heart, the aorta. The dimensions and flexibility of this vessel can in...
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RESEARCH
Using statistics to find the parts of the human genome that relate to our risk of heart and circulatory diseasesUniversity of Cambridge | Dr Adam Butterworth
Around 130 regions of DNA in the human genetic code are known to have an effect on our risk of heart attacks or strokes. However, in most cases we don’t yet understand how the genes in these regions have these effects. One way to tackle thi...
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RESEARCH
Identifying the specific genes responsible for antibody-associated vasculitisUniversity of Cambridge | Professor Kenneth Smith
Antibody-associated vasculitis (AAV) is a devastating autoimmune disease, where a person’s own immune cells attack the body and cause damage. The resulting blood vessel inflammation can lead to a blood clot in the lungs, kidney failure, or ...
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RESEARCH
Understanding the causes of inherited lymphoedemaSt George's, University of London | Dr Pia Ostergaard
As well as the circulatory system that transports blood around the body, we also have a second circulatory system called the lymphatic system. It is made up of a network of vessels carrying ‘lymph’ fluid containing protein, fats, water and ...
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RESEARCH
Understanding the role of hibernating cells in atherosclerosisUniversity of Cambridge | Dr Murray Clarke
Atherosclerosis is the build-up of fatty material inside arteries, and it causes most heart attacks and strokes. An important process in atherosclerosis is inflammation within the blood vessel wall. This is thought to be caused in part by d...
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RESEARCH
Studying t-tubule structure and function in normal and damaged heart muscleImperial College London | Dr Eva Rog Zielinska
The main pumping chambers of the heart, the ventricles, are made up of billions of muscle cells. For our hearts to pump, electrical signals must spread rapidly from the pacemaker within the heart to ‘activate’ the cells in the ventricles to...
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RESEARCH
What cell types ultimately form new blood vessels?University College London | Dr Alice Plein
Dr Alice Plein from University College London is studying how the cells lining blood vessels form as embryos develop. She is looking for ways to control new blood vessel growth during heart and circulatory diseases. As the embryo develop...
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RESEARCH
Developing a potential gene therapy to prevent heart failure after heart attackUniversity of Glasgow | Professor Stuart A Nicklin
During a heart attack, part of the heart muscle is starved of its oxygen supply. This can permanently injure the oxygen-starved area which, over time, may lead to heart failure. Current treatments to preserve the heart muscle after heart at...