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There are 3433 result(s) for coronary disease mortality
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RESEARCH
Fixing the heart’s electrical wiring system to prevent abnormal heart rhythms and heart failureUniversity of Manchester | Dr Halina Dobrzynski
The heart has an electrical wiring system called the ‘cardiac conduction system’ (CCS), which is responsible for the start and coordination of each heartbeat. When this system goes wrong it results in a slow heart rate – a type of arrhythmi...
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RESEARCH
Pilot study: supervised cardiac rehabilitation after aortic aneurysm repairSt George's, University of London | Mr. Peter Holt
Aortic aneurysms, if left untreated, can rupture, causing internal bleeding and sudden death. Many patients with heart or circulatory disease are currently offered formal cardiac rehabilitation – particularly vulnerable patients who have ha...
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RESEARCH
Could cMyC be a better marker than troponins for diagnosing heart attacks?King's College London | Professor Michael Marber
Every day, hundreds of people go to hospital with symptoms that could indicate a heart attack. Identifying and treating someone who is having a heart attack quickly is essential, to limit the damage it causes to their heart. Hospital doctor...
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RESEARCH
Can export control stop cells releasing von Willebrand factor?Queen Mary, University of London | Dr Thomas Nightingale
Dr Thomas Nightingale and his team at Queen Mary, University of London, are looking for ways to control levels of a protein called von Willebrand factor, or VWF, which is linked to heart and circulatory disease. When the body is injured,...
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RESEARCH
Can activation of AMPK in endothelial cells improve blood vessel health in people with diabetes?University of Glasgow | Dr Ian Salt
Dr Ian Salt and Dr Timothy Palmer at the University of Glasgow have been awarded a grant to investigate the role of a specific set of proteins in endothelial cells. Endothelial cells line blood vessels and are important in maintaining a nor...
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RESEARCH
Uncovering how blocking BACE1 protects blood vessels in type 2 diabetesUniversity of Leeds | Dr Paul Meakin
Circulatory diseases – those that affect our veins and arteries – are caused by damage to endothelial cells, which line our blood vessels. Among other effects, this damage stops vessels responding to signals that should keep blood pressure ...
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RESEARCH
Finding preventable causes of heart and circulatory diseasesUniversity of Cambridge | Professor John Danesh
Understanding the direct causes of heart and circulatory diseases would help to prevent more people dying from them. However, it can be difficult to distinguish whether something causes a particular disease, or happens to be more common in ...
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RESEARCH
Identifying and predicting which forms of titin are involved in cardiomyopathyUniversity of Liverpool | Dr Olga Mayans
The heart is made up of many different cell types and proteins that work together to produce every heart beat. One important protein is called titin. There are over 8,000 different versions of the titin gene and some of them don’t work prop...
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RESEARCH
Identifying the specific genes responsible for antibody-associated vasculitisUniversity of Cambridge | Professor Kenneth Smith
Antibody-associated vasculitis (AAV) is a devastating autoimmune disease, where a person’s own immune cells attack the body and cause damage. The resulting blood vessel inflammation can lead to a blood clot in the lungs, kidney failure, or ...
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RESEARCH
The largest ever study of dilated cardiomyopathyImperial College London | Professor Stuart Cook
Dilated cardiomyopathy (DCM) is a disease of the heart muscle where it becomes stretched, thin and weak. This means the heart is unable to pump blood around the body efficiently. Treatments are limited and around one fifth of people with DC...