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There are 88 result(s) for cholesterol
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RESEARCH
Using nanomaterials to lower cholesterolUniversity of Surrey | Dr Daniel Whelligan
Atherosclerosis, where blood vessels become ‘furred up’ and narrowed, is a major cause of death and disability in the UK. Statins are used to lower cholesterol for those with, atherosclerosis but they are not always well tolerated. There ar...
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RESEARCH
Which DNA changes cause cholesterol-like molecules to enter the blood?Queen Mary, University of London | Professor Carol Shoulders
Professor Carol Shoulders and her team at Queen Mary, University of London are identifying changes in DNA that put people at higher risk of heart and circulatory disease, and if there are ways they can lower their risk. Phytosterols are ch...
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RESEARCH
The effect of high cholesterol on neutrophilsImperial College London | Dr Marina Botto
Cholesterol is a fatty substance that is vital for normal functions in the body. However, when levels of harmful forms of cholesterol are too high, it can lead to fatty deposits building up in our arteries. This can block the flow of blood ...
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RESEARCH
Investigating how bad cholesterol is removed from the bodyUniversity College London | Dr Emmanuel Boucrot
When the levels of LDL (‘bad cholesterol’) are raised in the blood, our chances of developing coronary heart disease increase. Statin drugs lower cholesterol in the body by blocking its production in the liver. However, in response to this ...
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RESEARCH
Looking for a new way to lower cholesterolUniversity of Sheffield | Professor Endre Kiss Toth
Dr Endre Kiss Toth and his team at the University of Sheffield are looking for new ways to lower cholesterol levels in the blood to prevent arteries becoming blocked with fatty plaques, or atherosclerosis. Scientists have found that a prot...
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RESEARCH
Does cholesterol alert our immune system to atherosclerosis?University of Cambridge | Dr Meritxell Nus Chimeno
Atherosclerosis is the build-up of fatty material inside your arteries, causing them to harden and narrow, which can eventually trigger a heart attack or stroke. B cells are a type of immune cell whose role is to produce antibodies to help...
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RESEARCH
Understanding the role of LDL cholesterol in platelet activationUniversity of Hull | Professor Khalid Naseem
Professor Khalid Naseem from the University of Hull and Dr Michael Tomlinson from the University of Birmingham will spend 3 years studying the behaviour of tiny blood cells called platelets in the circulatory system. Although platelets are ...
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RESEARCH
How do cholesterol and platelets team up to cause blood vessel damage?University of Leeds | Professor Khalid Naseem
Professor Khalid Naseem and colleagues at the University of Hull are studying how ‘bad’ cholesterol teams up with platelets to cause blood vessel damage that contributes to atherosclerosis, the condition underlying coronary heart disease. ...
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RESEARCH
Using Big Data to detect side effects of statins, for better informed prescribingUniversity of Oxford | Dr Christina Reith
Statins are medicines that lower cholesterol levels and reduce the risk of heart attacks and strokes. These benefits have been proven in many clinical trials, including the BHF-funded Heart Protection Study. However, there is public concern...
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RESEARCH
Working out ways to reverse atherosclerosisUniversity of Oxford | Dr Gillian Douglas
Dr Gillian Douglas at the University of Oxford is working out if atherosclerosis, the process where arteries becoming furred up with fatty material and harden to form a plaque, can be reversed. Plaque rupture can lead to a heart attack o...