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  • RESEARCH

    Sorting apples from pears: do Wnt proteins determine body fat distribution?

    University of Oxford | Dr Constantinos Christodoulides

    BHF Intermediate Clinical Research Fellow Dr Constantinos Christodoulides is working out if proteins called Wnts affect a person’s risk of developing heart and circulatory disease. The location of body fat determines how it influences th...

  • RESEARCH

    Understanding how pericytes drive new blood vessel growth

    University of Bristol | Professor Paolo Madeddu

    Pericytes are cells that surround blood vessels and play an important role in the growth of new blood vessels (known as angiogenesis). When there is a reduction in blood supply (ischemia), the growth of new blood vessels limits the damage c...

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  • European Heart Network appoints BHF CEO as President

    Our Chief Executive Dr Charmaine Griffiths has been announced as the new President of the European Heart Network (EHN).

  • RESEARCH

    The athlete’s paradox, insulin resistance and diabetes

    University of Aberdeen | Professor Dana Dawson

    Dr Dana Dawson and her team at the University of Aberdeen are investigating the ‘athlete’s paradox’: why both obese people with diabetes and trained athletes have higher levels of lipids (fat) in their muscles, but with differing impacts on...

  • RESEARCH

    Working out how congenital heart defects develop

    University College London | Professor Peter Scambler

    Professor Peter Scambler and his team at University College London study the underlying causes of different types of congenital heart disease – a condition where the heart doesn’t form properly as it develops in the womb. Professor Scam...

  • RESEARCH

    Unravelling the effects of genetic variation in pulmonary hypertension

    Imperial College London | Dr Christopher Rhodes

    Over 9000 European people with rare diseases had their genomes sequenced as part of the UK’s BRIDGE project. One of diseases studied was pulmonary arterial hypertension (PAH) – high blood pressure in the lungs, which leads to heart failure....

  • Statins may counteract stress hormones in pregnant women

    BHF research suggests that statins could protect the hearts of babies in the womb from the adverse effects of their mother’s stress.

  • RESEARCH

    Computer assessment of patients for transcatheter aortic valve replacement

    University College London | Professor Silvia Schievano

    Diseases of the heart valves are common and, when serious, require treatment with open-heart surgery. Recently, a non-surgical technique for aortic valve replacement has been developed. Despite its success, only patients considered at high ...

  • RESEARCH

    Testing new treatments for CPVT

    University of Manchester | Dr Luigi Venetucci

    Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder characterised by the onset of irregular heart rhythm during exertion. This irregular heart rhythm (often a ventricular arrhythmia) can cause collapse and sud...