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RESEARCH
Which anti-platelet drug slows down atherosclerosis most effectively?King's College London | Professor Albert Ferro
Millions of people in the UK are living with coronary heart disease - the UK’s biggest killer. It caused by a process called atherosclerosis, when fatty plaques build up inside artery walls and the vessels become narrow. Clinical pharma...
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RESEARCH
Harnessing the diverse power of VEGF in blood vessel growthUniversity College London | Professor Christiana Ruhrberg
Problems with blood vessel contribute to heart attacks, strokes and blindness, and giving drugs to stimulate new vessel growth is a promising treatment for these conditions. One of the most effective treatments to stimulate blood vessel g...
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RESEARCH
Understanding the role of Pak3 protein in heart cell dysfunction and heart failureUniversity of Manchester | Dr Wei Liu
Heart failure – when the heart cannot pump blood around the body effectively – is a leading cause of death worldwide. Regardless of the initial cause, many changes take place in heart cells during the development of heart failure. Autopha...
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RESEARCH
How does JCAD raise the risk of coronary heart disease, and how can we combat it?University of Oxford | Dr Gillian Douglas
Oxford researchers are uncovering how a newly-discovered gene relates to heart disease. Studies of the human genome have spotlighted a new gene that raises the risk of coronary heart disease. The gene has been named JCAD and, with BHF fu...
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RESEARCH
Exploring the complex genetics behind congenital heart diseaseUniversity of Nottingham | Professor John David Brook
Congenital heart disease affects around 1 in 133 newborn babies. Genetics play a large part in this, and in many cases there are complex interactions between many different genes. A genetic test called an ‘array-CGH’ can reveal more about t...
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RESEARCH
Studying the miniscule cellular signals in heart failureUniversity of Oxford | Professor Manuela Zaccolo
Heart failure is a debilitating condition that often carries a poor prognosis. We know that a molecule in heart cells, called cAMP, is a lynchpin in several processes that go awry in heart failure. In fact, some current medicines already ta...