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  • RESEARCH

    How does a molecule called ATP prevent dangerous calcium build up in blood vessels?

    Royal Veterinary College, University of London | Dr Isabel Orriss

    Dr Isabel Orriss is studying a process called calcification, when bone-like deposits of a mineral called calcium phosphate build up in the arteries, heart valves and heart muscle tissue. Calcification often occurs in people with diabet...

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  • BHF wins top HR prize for innovative workplace strategy

    We took top prize for the Best Flexible Working Strategy at the prestigious HR Excellence Awards this week.

  • RESEARCH

    Answering fundamental questions about heart development

    University College London | Professor Peter Scambler

    Abnormalities in the heart and circulatory system (often called congenital heart disease) are the commonest defects that can be present at birth. Unlocking the genetic secrets behind how the heart develops in the growing embryo may not o...

  • RESEARCH

    Can people with dilated cardiomyopathy without symptoms stop taking their medication?

    Imperial College London | Professor Sanjay Prasad

    Supervised by Dr Sanjay Prasad, this Clinical Research Training Fellowship asks if it is safe to stop medication in people who have recovered from the heart muscle disease dilated cardiomyopathy (DCM). In DCM the heart doesn’t pump corre...

  • RESEARCH

    Designing drugs without heart side-effects

    University of Bristol | Professor Jules Hancox

    The heart’s ability to pump blood depends on co-ordinated electrical activity generated by molecules in heart cells called ‘ion channels’. One of these channels is called hERG, and is essential for normal heart function. However, many drugs...

  • RESEARCH

    Can a new test for heart attack save lives?

    University of Edinburgh | Professor Nicholas Mills

    Every year thousands of people in the UK are diagnosed as having had a heart attack. It is not always easy to confirm a heart attack has occurred, because the nature and severity of symptoms varies. One of the tests doctors use analyses blo...

  • RESEARCH

    How a South American plant can teach us about irregular heart rhythm

    Swansea University | Dr Mark Bannister

    Dr Mark Bannister and his team at the University of Swansea are studying a protein inside heart cells called the ryanodine receptor. The ryanodine receptor is a channel that releases calcium from stores inside the heart cells, providing the...

  • RESEARCH

    How does a protein called SIRT1 prevent harmful blood clot formation?

    Manchester Metropolitan University | Dr Sarah Jones

    Heart attacks and strokes occur when blood clots form and block the blood supply to the heart or brain. When blood vessels are damaged, small blood cells called platelets are activated and clump together to form a clot. In healthy blood ves...

  • RESEARCH

    Engineering a new window on artery health

    Imperial College London | Professor Mengxing Tang

    As blood flows through our arteries it exerts forces on the artery wall. The strength of these forces varies according to the shape of the vessel – whether it is straight or has bends or branches. We know that these forces affect how the ar...