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  • RESEARCH

    Testing if phosphodiesterases could treat atrial fibrillation

    University of Manchester | Dr Katharine Dibb

    Dr Katharine Dibb and her colleagues at the University of Manchester are investigating a new way to treat the most common irregular heart rhythm, atrial fibrillation (AF). AF can lead to a person having a stroke or heart attack. Calciu...

  • RESEARCH

    Interactions with VEGF – a potential protein for mending broken hearts

    University College London | Professor Ian C Zachary

    Heart and circulatory disease is Britain’s biggest killer – in 2009 it was responsible for one in three deaths. Endothelial cells line our blood vessels ensuring that our circulatory system functions normally. It is often disruption of thes...

  • RESEARCH

    Keeping blood vessels healthy in diabetes

    University of Leeds | Professor Mark Kearney

    Narrowing of the blood vessels is a major problem for people with diabetes and can cause high blood pressure and predispose to heart attack, stroke or peripheral arterial disease. Professor Mark Kearney and colleagues from the University o...

  • RESEARCH

    Finding genes that tell left from right

    University of Leeds | Professor Colin Johnson

    Cilia are finger-like projections from cells that act as a cellular antenna to detect and respond to chemical or mechanical cues. Cilia are responsible for the development of the normal left-right asymmetry in the embryo, where different or...

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  • RESEARCH

    Understanding heart scarring in atrial fibrillation

    Queen's University Belfast | Dr David Simpson

    Atrial fibrillation (AF) – abnormal beating of the heart – often occurs because scar tissue has formed in the heart. This process is called fibrosis. The aim of this project is to understand more about the cells that cause fibrosis, to deve...

  • RESEARCH

    Why does heart disease occur more frequently in people with rheumatoid arthritis?

    University of Manchester | Dr John Bowes

    Rheumatoid arthritis (RA) is an inflammatory condition affecting the joints. People with RA are at a higher risk of coronary heart disease (CHD) – when the arteries supplying the heart with blood get clogged up with fatty deposits. CHD caus...

  • RESEARCH

    Answering fundamental questions about heart development

    University College London | Professor Peter Scambler

    Abnormalities in the heart and circulatory system (often called congenital heart disease) are the commonest defects that can be present at birth. Unlocking the genetic secrets behind how the heart develops in the growing embryo may not o...

  • Catecholaminergic polymorphic ventricular tachycardia (CPVT) 

    CPVT is a rare inherited heart rhythm disturbance found in young people and children.

  • Spending less time watching TV could cut coronary heart disease risk

    Research has found that people who spend more time watching TV are at higher risk of developing coronary heart disease, regardless of their genetic makeup.