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  • RESEARCH

    How does protein build-up cause different types of heart damage?

    University College London | Dr Marianna Fontana

    Amyloidosis of the heart occurs when abnormal protein molecules (amyloid) produced by bone marrow builds up in heart muscle. The amyloid causes stiffening of the heart muscle, interferes with the heart’s electrical system and reduces blood ...

  • RESEARCH

    Improving patient outcome after transcatheter aortic valve replacement surgery for aortic stenosis

    University College London | Professor Gaetano Burriesci

    Dr Gaetano Burriesci has been awarded a PhD studentship to work out how to improve patient outcome following transcatheter aortic valve implantation (TAVI), an operation where a new valve is manoeuvred up the femoral artery and inserted ins...

  • RESEARCH

    Is junk DNA important in heart disease?

    Queen Mary, University of London | Dr Andrew Smith

    In this Intermediate Basic Science Fellowship Dr Andrew Smith from University College London will study regions of our DNA to find out why coronary heart disease often runs in families. We know that there are regions of our DNA that are lin...

  • RESEARCH

    Centre for Cardiovascular Drug Target Discovery

    University of Oxford | Professor Sir Peter Ratcliffe

    Atherosclerosis is the build-up of fatty plaques in the walls of blood vessels which causes coronary heart disease. Pioneering work by BHF funded scientists is underpinning efforts to identify new medicines that can help control and prevent...

  • RESEARCH

    Damage limitation after a heart attack

    University College London | Professor Sean Davidson

    Dr Sean Davidson is studying how we can protect the heart from further damage after a heart attack to prevent progression to heart failure During a heart attack, the heart is starved of blood carrying oxygen. The only way to protect the ...

  • RESEARCH

    What controls how heart muscle cells contract?

    Cardiff University | Dr Nia Thomas

    Dr Nia Lowri Thomas and her team at Cardiff University are studying the processes that control how heart muscle cells contract during each heartbeat and what goes wrong in abnormal heart rhythms. For heart muscle cells to contract, calci...

  • RESEARCH

    Searching for a safer anti-clotting drug by studying a protein called Factor XII

    University of Nottingham | Professor Jonas Emsley

    People who have survived a heart attack or stroke tend to be at high risk of having another one. To try to prevent a repeat event, doctors prescribe certain medicines. These often include anticoagulant, also called anti-clotting, drugs suc...

  • RESEARCH

    How developing heart cells find their identity

    University of East Anglia | Professor Andrea E Munsterberg

    Professor Andrea Munsterberg is working out which molecules and signals play a role in heart formation in the developing embryo. Early on, immature cells that will form the heart, called progenitor ‘master’ cells, are instructed by signa...

  • RESEARCH

    Can genetics help us tailor blood pressure treatment?

    University of Glasgow | Professor Sandosh Padmanabhan

    Professor Sandosh Padmanabhan and colleagues at the University of Glasgow are studying new ways to treat people with uncontrolled hypertension, or high blood pressure. Nearly half of those treated with current blood pressure lowering drugs ...

  • RESEARCH

    Understanding how zinc controls blood clotting

    Anglia Ruskin University | Dr Nicholas Pugh

    Blood clots form when small cells in the blood called platelets are activated and stick together. Controlling when platelets become activated is essential to ensure clotting happens when it is needed - for example, after injury - whilst lim...