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RESEARCH
PKN1 protein as an important regulator of platelet stickinessUniversity of Bristol | Professor Alastair Poole
Professor Alastair Poole and colleagues at the University of Bristol are going to investigate a new protein called PKN1, which looks promising as an important regulator of platelet stickiness. Platelets are small cells that flow around...
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RESEARCH
How our nerves control fat cell functionUniversity of Manchester | Professor Anthony Heagerty
Professor Anthony Heagerty and his team at the University of Manchester are studying how obesity increases a person’s risk of diabetes and high blood pressure. Almost a quarter of UK adults are obese, but we don’t fully understand how obesi...
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RESEARCH
Why does heart block occur at night, especially in athletes?University of Manchester | Dr Halina Dobrzynski
The rate and rhythm of the heartbeat changes between night and day. In particular, at night there can be long pauses between heartbeats, known as ‘heart block’. This occurs in a specialised part of the heart called the atrioventricular (AV)...
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RESEARCH
Investigating why some coronary artery disease patients don’t benefit from bypass surgeryUniversity College London | Dr Charlotte Manisty
Heart failure affects over half a million people in the UK. Often, it’s caused by coronary heart disease, when the arteries supplying the heart muscle become narrowed or blocked. One of the most effective treatments for coronary heart disea...
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RESEARCH
Understanding how mast cells drive inflammation in blood vesselsQueen Mary, University of London | Professor Sussan Nourshargh
Inflammation is an essential part of the body’s defence system against viruses and bacteria. It is also an underlying cause of many heart and circulatory conditions like atherosclerosis. Atherosclerosis is the build-up of fatty substances i...
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RESEARCH
Why is pulmonary arterial hypertension more common in women?University of Glasgow | Professor Margaret MacLean
Pulmonary arterial hypertension is a rare but fatal disorder of high blood pressure in the blood vessels that supply the lungs. The condition is caused by the narrowing of these vessels. Although treatments are available, they are not fully...
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RESEARCH
Looking for treatments for essential thrombocythaemiaUniversity of Cambridge | Dr Cedric Ghevaert
People with the condition essential thrombocythaemia (ET) have too many platelets in the blood and are at increased risk of cardiovascular events. This is because an excess of platelets can lead to excessive clotting and blockage of the ve...
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