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  • RESEARCH

    How intensively should we treat blood pressure in people with disease of the small blood vessels in the brain?

    University of Cambridge | Professor Hugh Markus

    Disease of the small blood vessels in the brain is an important cause of stroke and is the most common cause of cognitive impairment and dementia. High blood pressure is the major factor causing small vessel disease of the brain. We know t...

  • RESEARCH

    How platelet numbers and stickiness are controlled in blood clotting

    University of Birmingham | Professor Yotis Senis

    Professor Yotis Senis is studying platelets, which are the cells that help our blood to clot. Platelets are small cells that plug holes in damaged blood vessels and prevent excessive bleeding. But they can also form clots inside blood ve...

  • RESEARCH

    Blocking inflammation in arteries to prevent heart disease

    University of Strathclyde | Professor Robin Plevin

    CXCL12 is a molecule that causes inflammation and has been linked to the development of heart and circulatory diseases. Researchers are now interested in whether they can stop it working in blood vessel cells and whether this might help pre...

  • RESEARCH

    Testing a new strategy to treat inflammation in heart disease

    University of Cambridge | Dr Xuan Li

    Dr Xuan Li from the University of Cambridge is looking for ways to reduce inflammation, a process which is involved in the build-up of fatty plaques inside arteries. When these plaques rupture they can block blood vessels, causing a life-th...

  • RESEARCH

    New magnetic resonance technology for the University of Oxford

    University of Oxford | Professor Damian Tyler

    Heart failure is a debilitating condition and can cause breathlessness, making it almost impossible for patients to do even simple exercise such as walking up stairs. During heart failure, changes occur in heart muscle. BHF-funded scient...

  • RESEARCH

    Can a drug called allopurinol help people with heart and lung disease?

    University of Dundee | Professor Allan Struthers

    Chronic obstructive pulmonary disease (COPD) is a condition where the airways become inflamed and narrowed, causing difficulty breathing. It is a common condition, which affects people’s daily lives. Many people with COPD develop a form of ...

  • RESEARCH

    Monitoring heart valve disease by improving the reliability of echocardiography

    Imperial College London | Professor Darrel Francis

    People with moderately narrowed or leaky heart valves, mostly the mitral valve or aortic valve, need to have ultrasound scans to determine when they need an operation. But the technique used to monitor severity, called echocardiography, alt...

  • RESEARCH

    Harnessing the body’s natural defences against blood vessel damage

    University of Sheffield | Dr Alfred Thompson

    Pulmonary arterial hypertension (PAH) is a devastating condition caused when the blood vessels in the lung become progressively narrower. This causes increased blood pressure in the lungs and can lead to heart failure. This abnormal narrow...

  • RESEARCH

    How does COPD increase the risk of heart failure?

    University of Manchester | Dr Christopher Miller

    Chronic obstructive pulmonary disease (COPD) is the name for a group of conditions that cause severe breathing difficulties. A third of people with COPD also have heart failure. You might expect this to be because the two diseases share ris...

  • Needle phobia: how to get over your fear of needles

    Read our practical tips to help you overcome needle phobia - from how to prepare for your appointment, to techniques you can use while you’re there.