Understanding amyloid deposition in the cardiovascular system
Amyloid is a substance made up of a mixture of proteins that have folded abnormally and solidified together. Amyloid can build up in tissues and organs such as the heart and the aorta. Cardiovascular amyloid is most common in people over the age of 50 and can cause heart failure and heart rhythm disturbances. In this Intermediate Basic Science Fellowship Dr Madine will investigate how amyloid is formed and builds up in the heart and blood vessels. She will study the structures of the amyloid protein mixtures, which will help to design drugs that could block their interactions and stop amyloid forming.
Project details
| Grant amount | £732,454 |
|---|---|
| Grant type | Fellowships |
| Application type | Intermediate Basic Science Research Fellowship |
| Start Date | 01 May 2013 |
| Duration | 6 years, 7 months |
| Reference | FS/12/61/29877 |
| Status | Complete |
