The role of endothelial BAMBI in haemostasis and thrombus stability
Heart attacks and strokes are caused by clots forming inside the blood vessels supplying the heart or brain. BAMBI is a protein on the surface of the cells that line our blood vessels called endothelial cells, and on the surface of platelets – cells that circulate in the blood and are important for clotting. Dr Isabelle Salles-Crawley from Imperial College London has recently found that, in mice, BAMBI protein in the cells lining blood vessels is important for normal blood clotting, but we don’t know how it does this. The BHF has now awarded Dr Salles-Crawley a grant to study this process in more detail and to find out how BAMBI influences endothelial cells. This research will further our understanding of blood clotting and may reveal new ways to prevent unwanted blood clotting in the future.
Project details
| Grant amount | £150,800 |
|---|---|
| Grant type | Project Grants |
| Application type | Project Grant |
| Start Date | 11 May 2015 |
| Duration | 2 years |
| Reference | PG/14/90/31219 |
| Status | Complete |
