The novel role of miR-15 family in extracellular matrix remodelling in the vasculature
Dr Anna Zampetaki at King's College London has gathered evidence that a MicroRNA, miR-195 is involved in abdominal aortic aneurysms (AAA). MicroRNAs alter the levels of proteins in and around cells (in the extracellular matrix), and by investigating the role of miR-195, Dr Anna Zampetaki aims to evaluate its potential as a therapeutic target. The group will study miR-195 function using cells and animal models of AAA. The data gathered will be analysed using a systems biology approach and will be used to assess the impact of miR-195 on the extracellular matrix and aneurysm formation.
Project details
| Grant amount | £432,389 |
|---|---|
| Grant type | Fellowships |
| Application type | Intermediate Basic Science Research Fellowship |
| Start Date | 01 July 2013 |
| Duration | 5 years |
| Reference | FS/13/18/30207 |
| Status | Complete |
