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Finding the best blood pressure levels in children with chronic kidney disease

Dr Manish Sinha (lead researcher)

King's College London

Start date: 07 January 2013 (Duration 3 years)

The Hypertension Optimal Treatment in children with chronic KIdney Disease study: The HOT-KID study - A randomised trial to compare effects of aggressive versus standard targets in blood pressure on target organ damage in children with CKD

Kidney disease is one of the most common chronic diseases that can affect children. Although effective treatments are available, children with kidney disease are at high risk of developing heart disease as young adults. High blood pressure caused by kidney disease is thought to damage the heart and blood vessels. Dr Manish Sinha and his research team at King’s College London are investigating whether controlling blood pressure (in children with kidney disease) to a level lower than that currently recommended will help prevent damage to the heart and blood vessels later in life. The children will be followed for two years to see whether this intensive strategy reduces early signs of heart and blood vessel damage.

Project details

Grant amount £361,373
Grant type Project Grants
Application type Project Grant
Start Date 07 January 2013
Duration 3 years
Reference PG/11/90/28994
Status In Progress
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