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New scan of small blood vessels could help spot people with angina

Professor Colin Berry (lead researcher)

University of Glasgow

Start date: 01 January 1900 (Duration 3 years)

The clinical utility of cardiac magnetic resonance imaging in patients with angina but no obstructive coronary disease (CorCMR): A diagnostic study and nested randomised trial

Standard NHS scans of the heart (angiograms) cannot pick up the smaller blood vessels in the heart. This means in some people with angina, problems affecting the smaller blood vessels may be missed and scans can appear normal, potentially leaving them at increased risk of heart attack and stroke. It is not uncommon for people to need to go back to their doctor multiple times with unexplained symptoms, causing frustration and anxiety. In this study, 280 patients with angina, who have recently had a heart angiogram that showed clear heart arteries, are being invited to have a new type of heart scan called pixel-mapping magnetic resonance imaging (MRI). This new scan measures blood flow in the heart. Patients will be randomly put into one of two groups: one where the results of the new scan are used to guide treatment, and another where the results are not disclosed. Professor Colin Berry’s team will then be able to test whether the MRI results lead to changes in the diagnosis and treatment of these people. They will also conduct surveys to see whether the new scan improves patient wellbeing and compare the costs of the two scans. The research could help to improve the treatment of people with angina that is caused by complications with the small blood vessels.

Project details

Grant amount £322,031
Grant type Project Grants
Application type Project Grant
Start Date 01 January 1900
Duration 3 years
Reference PG/19/28/34310
Status In Progress
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