Selecting Rhythm or Rate Control in Patients with both Atrial Fibrillation and Heart Failure
Atrial fibrillation (AF), an irregular heart rhythm in the upper two chambers of the heart, and heart failure (HF) often occur in people at the same time. AF can contribute to HF or can be caused by it, but it is not always clear to doctors which condition occurred first. Two treatment options are available for people with both AF and HF. In some people, AF itself is not treated but drugs to slow the heart rate are prescribed, and in others their AF is treated by restoring the heart’s normal rhythm. However, doctors are not currently able to confidently predict which people will respond best to the different treatment options available. Dr Steven Niederer and team at King’s College London will use clinical data from people with AF and HF to develop computer simulations of their heart condition and how they responded to treatment. They will use this information to predict the response of other patients to different treatments, then compare the predictions with people’s real-life response to treatment. They hope that this research will provide a better understanding of when control of the heart rate or the heart rhythm is best and which people will benefit most from each type of treatment.
Project details
| Grant amount | £761,196 |
|---|---|
| Grant type | Chairs & Programme Grants |
| Application type | Programme Grant |
| Start Date | 01 January 1900 |
| Duration | 5 years |
| Reference | RG/20/4/34803 |
| Status | In Progress |
