How does carbon monoxide affect the normal heart beat?
Regulation of cardiac ERG K+ channels by carbon monoxide
Chris Peers (lead researcher)
Leeds, University of
Start date: 06 January 2014 (Duration 3 years)
Carbon monoxide inhalation is the most common form of death by poisoning and can cause dangerous disruption to heart rhythm. Professor Chris Peers and co-workers based at the University of Leeds are carrying out BHF-funded research into the effects of carbon monoxide poisoning on the heart. Usually, our heartbeat is a coordinated electrical impulse that spreads through the heart. However, carbon monoxide poisoning commonly disrupts this electrical wave, leading to heart-rhythm abnormalities. The research group will focus on the effect of carbon monoxide molecules on sodium and potassium in the heart. These chemicals help to control the coordinated electrical impulse involved in each heartbeat. Understanding more about how carbon monoxide causes such damage to the heart is necessary to developing treatment for poisoned individuals.
||06 January 2014
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