A trial of peritoneal dialysis for advanced heart failure and chronic kidney disease

PD-HF: a trial of peritoneal dialysis for patients with advanced heart failure and stage 3-4 chronic kidney disease

Maarten Taal (lead researcher)

Nottingham,University of

Start date: 01 January 2016 (Duration 2 years 8 months)

In advanced heart failure and moderate chronic kidney disease, symptoms caused by fluid retention are the most common reason for hospital admissions. Symptoms caused by fluid retention are the most common reason for hospital admissions, and drug treatments are often less effective in those with kidney disease.

Thanks to a new grant, researchers at the University of Nottingham will carry out a clinical trial in 130 patients to find out whether removing this excess fluid from the body using a type of dialysis called peritoneal dialysis works better than the best drug treatments for people with advanced heart failure and chronic kidney disease.

During peritoneal dialysis, a small flexible tube, known as a catheter, is attached to an incision in the abdomen. Dialysis fluid is then pumped into the space that surrounds the peritoneum (the thin sheet of tissue that lines the inside of the abdomen).As blood moves through the peritoneum, waste products and excess fluid are moved out of the blood and into the dialysis fluid. If this and larger trials prove successful, peritoneal dialysis could become a treatment option for people with heart failure and kidney disease in the future.

Project details

Grant amount £251,261
Grant type Project Grant
Start Date 01 January 2016
Duration 2 years 8 months
Reference PG/13/27/29864
Status In progress

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