MURF2: An overlooked nuclear player in cardiac development and remodelling?
In 2011 there are over three quarters of a million people living with heart failure in the UK. This condition reduces the pumping function of the heart, which can make even day to day activities almost impossible, disturb heart rhythm and shorten life-expectancy. Heart muscle may try to respond to the extra stress it is placed under by increasing or decreasing the activity of proteins that drive the muscle to contract. A team from the BHF Centre of Research Excellence at King’s College London is interested in a protein, called MURF2, which is capable of regulating the activity of other contractile proteins. Understanding more about the function of MURF2 in healthy and failing hearts could lead to vital new treatments for heart failure.
Project details
| Grant amount | £243,217 |
|---|---|
| Grant type | Project Grants |
| Application type | Project Grant |
| Start Date | 01 February 2012 |
| Duration | 3 years |
| Reference | PG/11/127/29322 |
| Status | Complete |
