Using computer simulations to help with the treatment of children with congenital heart disease

Large scale validation of computer simulations for personalised cardiovascular treatments in congenital heart disease

Claudio Capelli (lead researcher)

University College London

Start date: (Duration 3 years)

Computer simulations could be an extremely valuable tool for visualising, testing and planning surgery in babies and children born with heart defects (known as congenital heart diseases). However, while the technology is ready, the technique has not yet made it into widespread practice. This is because large studies haven’t been done to prove its accuracy, the process is laborious and specialist experts are needed. One hospital that already uses computer simulations to inform and plan heart treatments is Great Ormond Street Hospital (GOSH). They have great confidence in the technique and want to encourage others to take advantage of it for the benefit of more children. The researchers from UCL and GOSH will take their patient-specific computer models and test how accurate they are on 200 previous cases of congenital heart disease, to provide evidence as to whether their model can diagnose these heart defects. The team will also attempt to improve the process of computer simulation, by testing new techniques and software that could significantly speed up and simplify the creation of computer models of the heart. The team hope that this project will lead to more children benefiting from a personalised approach to their congenital heart defects as surgeons work with families to decide on the best treatment.

Project details

Grant amount £183,422
Grant type Project Grant
Start Date
Duration 3 years
Reference PG/17/6/32797
Status In progress

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