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Harnessing the power of data to improve our understanding of diabetes

Professor Nish Chaturvedi (lead researcher)

University College London

Start date: 01 April 2017 (Duration 5 years)

Glycaemia and chronic disease: harnessing UK Biobank and eHealth linkage to quantify risks, explore mechanisms and determine treatment impacts (Joint funding with Diabetes UK)

People living with diabetes can develop long term consequences of their condition, including heart failure, cancer and dementia. In addition to those diagnosed with diabetes, there are millions of adults living in the UK with raised blood sugar (hyperglycaemia), for whom the long-term health risks are unclear. Professor Chaturvedi and her team will use the unprecedented quality of medical data now available to understand and quantify the risks associated with diabetes and hyperglycaemia. The team will analyse medical measurements taken from 500,000 volunteers through the UK Biobank programme, and will cross-reference these against medical records. They want to assess whether the blood sugar thresholds for diagnosis of diabetes are good enough. And they’re looking for clues as to why some people – including women and ethnic minority groups – are more susceptible to getting diabetes-related diseases. They will then try to find out whether some diabetes medicines could be increasing the risk of developing other health problems. They will gain unique insights from the quality and quantity of data provided by Biobank, which could change the diagnosis and care of people with diabetes. Their findings could also reveal ways of reducing the long term health complications associated with the condition. This important programme of work has been made possible by a funding partnership between the BHF and Diabetes UK.

Project details

Grant amount £349,068
Grant type Chairs & Programme Grants
Application type Special Project
Start Date 01 April 2017
Duration 5 years
Reference SP/16/6/32726
Status In Progress
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