How heart failure affects heart muscle cells
Professor Andrew Trafford (lead researcher)
University of Manchester
Start date: 01 November 2012 (Duration 5 years)
Dysfunctional β-Adrenergic Signalling in Heart Failure: Impact on Cellular Calcium Homeostasis and Role as a Therapeutic Target
When you exercise or are frightened your heart pumps much harder due to the release of certain chemicals in the body. In heart diseases such as heart failure the muscle cells in the heart which are responsible for the pumping of blood fail to work harder when exposed to these chemicals. This research will study the reasons why the muscle cells of the heart do not respond properly to these chemicals, and how certain treatments used in heart failure affect heart cells.
Project details
Grant amount | £1,186,190 |
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Grant type | Fellowships |
Application type | Senior Basic Science Research Fellowship |
Start Date | 01 November 2012 |
Duration | 5 years |
Reference | FS/12/57/29717 |
Status | Complete |