The effects of controlling a person’s blood pressure following brain haemorrhage and stroke

Does blood pressure variability (BPV) affect outcome after stroke due to intracerebral haemorrhage?(Dr Thomas Moullaali)

Rustam Al-Shahi Salman (lead researcher)

Edinburgh, University of

Start date: 01 January 2018 (Duration 3 years)

Professor Rustam Al-Shahi Salman and colleagues at the University of Edinburgh are investigating if carefully controlling a person’s blood pressure improves their outcome following a stroke caused by a brain haemorrhage. Currently, it is known that lowering blood pressure prevents the likelihood of a person having another stroke. However, a person’s blood pressure measurements can vary in the days after a haemorrhage, and this variability may worsen the outcome for these patients.

In this project, a student working with Professor Salman will follow 7,000 patients to determine whether blood pressure changes in the days after brain haemorrhage influences their recovery three months later. They will then, in a smaller group of 450 patients, study if blood pressure changes, in the weeks and months after a brain haemorrhage, influence the likelihood of a further stroke in the years afterwards. Finally, the team will ask 50 people who have had a brain haemorrhage to record their blood pressure and measure variability for six months after they have been discharged from hospital. They want to see if this task influences how often people see their doctor and if their blood pressure treatment is altered as a result.

This research will reveal if controlling blood pressure variability could help doctors improve outcomes for their patients who survive a brain haemorrhage.

Project details

Grant amount £168,553
Grant type Fellowship
Application type Clinical Research Training Fellowship
Start Date 01 January 2018
Duration 3 years
Reference FS/17/53/33119
Status In progress

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