New scanning methods to reveal cause and effect in heart disease
Professor Robin P Choudhury (lead researcher)
University of Oxford
Start date: 01 March 2016 (Duration 3 years)
Development and validation of fused 3D coronary arteriograms with multimodal MRI
Professor Robin Choudhury and his colleagues at the University of Oxford are working out how to combine imaging techniques so they can be used to tell doctors what has happened to heart muscle after a heart attack, and what caused it. New cardiovascular magnetic resonance, or CMR imaging techniques can assess heart and blood vessel structure and function. They can reveal information about heart muscle function, composition, swelling (oedema) after injury and any obstructions in smaller blood vessels. But this only provides information about the heart muscle in isolation, and will not reveal what has caused the problem in the coronary arteries. Understanding the full story could help patients with blockages in several blood vessels or in different places in the same blood vessel. In this project, Professor Choudhury will develop new methods combining two complementary heart imaging techniques to reveal more about the blood supply to the heart muscle and about the muscle that receives that supply, at the same time. They will integrate three-dimensional models of branching heart arteries, taken during coronary arteriography, with three-dimensional MR scans of the heart. This research could reveal new ways for doctors to examine the heart and the blood vessels simultaneously, helping doctors make a more accurate diagnosis and decide treatments their patients should receive.
Project details
Grant amount | £153,389 |
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Grant type | Project Grants |
Application type | Project Grant |
Start Date | 01 March 2016 |
Duration | 3 years |
Reference | PG/15/110/31936 |
Status | Complete |