Analysing MRI scans of people taking part in UK Biobank

Creation of cardiovascular magnetic resonance imaging reference standard for the UK Biobank imaging resource

Steffen Petersen (lead researcher)

Queen Mary, University of London

Start date: 01 June 2015 (Duration 3 years)

Research studying large populations has revolutionised cardiology and prevention strategies by identifying well-established cardiovascular risk factors, such as smoking, obesity and lack of physical activity. Between 2006 and 2010, 500,000 people aged between 40-69 years from across the UK signed up to take part in UK Biobank, a powerful resource to help scientists discover why some people develop particular diseases and others do not. UK Biobank already holds a vast amount of data on the health of its participants.

UK Biobank has now started a large heart imaging study in one fifth of the people taking part - 100,000 people. Pictures of their heart size, heart function, heart weight and stiffness of blood vessels will be taken using magnetic resonance imaging (MRI). The BHF has awarded a grant to Professor Steffen Petersen at Queen Mary, University of London to analyse the first 5,000 heart MRI scans. This work will help to develop new and faster image analysis techniques for the remaining 95,000 images to be analysed. The project will also develop a gold standard against which future automated magnetic resonance imaging analysis can be measured. Heart MRI scans, when used in the context of existing data in the UK Biobank resource, will help investigate heart health on a larger scale and in greater detail than has been done before.

Project details

Grant amount £154,090
Grant type Project Grant
Start Date 01 June 2015
Duration 3 years
Reference PG/14/89/31194
Status In progress

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