Autonomic modulation of ventricular arrhythmias in heart failure
Heart attack results in heart failure which is a common condition associated with premature death, often due to heart rhythm disturbances (arrhythmias). It is thought that after a heart attack the nerves that control the heart beat (the autonomic nerves) could be altered, which may predispose to heart rhythm disturbances. This project will investigate the role of autonomic nerves in the development of arrhythmias that are seen in heart failure. The researchers will study the interaction of the two branches of autonomic nerves - sympathetic and parasympathetic nerves - to see if an imbalance between these two branches causes arrhythmia in normal conditions and in a heart failure model. The project will determine how autonomic nerves in the heart are altered as a result of a heart attack and how the altered nerve activity influence dangerous heart rhythms in heart failure.
Project details
| Grant amount | £221,902 |
|---|---|
| Grant type | Fellowships |
| Application type | Clinical Research Training Fellowship |
| Start Date | 07 January 2013 |
| Duration | 3 years |
| Reference | FS/12/52/29629 |
| Status | Complete |
