Should people who’ve had a cardiac arrest be treated in heart attack centres?

A randomised trial of expedited transfer to a cardiac arrest centre for non-ST elevation out of hospital cardiac arrest. The ARREST trial. ISRCTN 96585404

Simon Redwood (lead researcher)

King's College London, St Thomas' Hospital

Start date: 01 May 2017 (Duration 5 years)

A cardiac arrest is a serious condition where the heart stops beating. Only one in 10 people who have a cardiac arrest out of hospital survive. In this clinical trial conducted across London, Professor Simon Redwood and his team will assess if a new way of responding to this medical emergency could give people a better chance of survival. Currently, cardiac arrest patients are taken quickly by ambulance to the nearest A&E. But evidence suggests that people may have a better chance of survival if they go straight to a specialist hospital – a Cardiac Arrest Centre - with a team experienced in treatment of this condition. Most of the time cardiac arrest is caused by a heart attack, so these hospitals would have the equipment and skills to unblock arteries as soon as possible.  In this study, half of eligible patients (people who’ve had a cardiac arrest but have not obviously had a heart attack) attended by a London Ambulance Service Paramedic involved in the trial will be taken to the nearest A&E as normal. The other half will go straight to the nearest Cardiac Arrest Centre. Patients’ survival and health up to one year after cardiac arrest will be recorded. The results will inform best practice for treating cardiac arrest all across the UK, and could save many thousands of lives into the future.

Project details

Grant amount £950,497
Grant type Clinical Study
Start Date 01 May 2017
Duration 5 years
Reference CS/16/3/32615
Status In progress

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