Most of us have experienced pain – a headache, a pulled muscle or injury from a trip, slip or fall – that could be managed by over-the-counter painkillers. However, an increasing number of people are living with long-term pain as a result of conditions such as arthritis. In these cases, painkillers only available by prescription are always more effective.
Pain is a broad and complex area of healthcare. It covers short-term (acute) pain, such as headaches, pulled muscles and minor injuries, and long-term (chronic) pain, which can include inflammation of the joints.
Here we explain about varieties of painkiller and their uses and side effects.
Over-the-counter painkillers
Paracetamol
Uses |
Alternative uses |
Interactions with other medication |
Possible side effects |
Mild pain (acute or chronic) |
To reduce temperature |
Anticoagulants (eg warfarin) |
Rarely, a rash or swelling |
Aspirin
Uses |
Alternative uses |
Interactions with other medication |
Possible side effects |
Mild pain associated with inflammation
(acute or chronic) |
To prevent blood clots forming |
Ibuprofen
Some diuretics (water tablets)
Antidepressants |
Indigestion
Vomiting
Bleeding in the stomach
|
Ibuprofen
Uses |
Alternative uses |
Interactions with other medication |
Possible side effects |
Mild pain (acute or chronic) |
To reduce raised temperature
To reduce inflammation
|
Aspirin
Anticoagulants
(both warfarin and NOACs)
|
Indigestion
Heartburn
Stomach ulcers/
gastrointestinal
tract bleeding
|
Prescription-only painkillers
Co-codamol, co-dydramol, co-codaprin
Uses |
Alternative uses |
Interactions with other medication |
Possible side effects |
Mild to moderate pain (acute or chronic)
(Milder forms are available over-the-counter) |
None |
Antidepressants |
Constipation
Nausea
Diarrhoea
|
COXIBs (eg celecoxib, etoricoxib)
Uses |
Alternative uses |
Interactions with other medication |
Possible side effects |
Head/tooth/back ache, sprains
Arthritis, gout
Kidney/gallstones
Pain following major surgery
Neuralgia
|
Pain associated with cancer |
Aspirin
Anticoagulants
|
High blood pressure
Reduced kidney function
Stomach or duodenal ulcers
|
Opiates (eg codeine, tramadol, oxycodone, morphine)
Uses |
Alternative uses |
Interactions with other medication |
Possible side effects |
Moderate to severe pain
(acute or chronic), commonly used
in end-of-life care
|
To relieve breathlessness
in heart failure |
Antidepressants
Antihistamines
Some blood pressure
medications
|
Nausea
Vomiting
Itching
Constipation
Drowsiness
Dry mouth
|
Can I get help with paying my prescription?
Medical prescriptions are free in Northern Ireland, Scotland and Wales. They are also free for people in England who meet certain criteria, including people who are:
- under 16 or over 60
- receiving Income Support, JSA, ESA or Universal Credit
- pregnant
- 16-18 and in full-time education
- and/or have certain health conditions, including a continuing disability or diabetes that can't be controlled with diet.
If you aren’t entitled to free prescriptions for your medicines you might be able to save money by buying a Prescription Prepayment Certificate (PPC).
getting help with prescription costs