Hypertrophic cardiomyopathy                 

Adult & child hands - HCM is passed on through familiesHypertrophic cardiomyopathy (HCM) is an inherited disease of your heart muscle, where the muscle wall of your heart becomes thickened.   

It is a genetic condition caused by a change or mutation in one or more genes and is passed on through families. Each child of someone with HCM has a 50 per cent chance of inheriting the condition.

About 1 in 500 of the UK population has the condition, although most people who have it have few symptoms.

How does it affect my heart?

If you have HCM, the muscular wall of your heart - the myocardium - becomes thickened, making the heart muscle stiff.

This thickening makes it harder for your heart to pump blood out of your heart and around your body.

How thick your muscle is, and how much of your muscle is affected, varies from one person to another. The left ventricle (one of your heart's four chambers) is almost always affected, and in some people the muscle of the right ventricle also thickens.

What are the symptoms?

Common symptoms include:

  • Shortness of breath
  • Chest pain
  • Palpitations
  • Light headedness and fainting

You may find that you never have any serious problems related to your condition, and with treatment, your symptoms should be controlled. However some people may find that their symptoms worsen or become harder to control in later life.

The area of heart muscle that is affected by HCM and the amount of stiffening that occurs will determine how the symptoms affect you.

For some people, a number of other conditions can develop as a result of having HCM. These may include:

How is HCM diagnosed?

The most common tests for cardiomyopathy are an ECG, which records the electrical activity of your heart, and an echocardiogram which show the pumping action of your heart. 

Your doctor may also arrange for you to have an exercise test, angiogram or MRI scan.

How is HCM treated?

At present there is no cure for HCM, but treatments are available to help control your symptoms and prevent complications. Your treatment will depend on how your heart is affected and what symptoms you have.

You may need:

  • Medicines – to help control your blood pressure, abnormal heart rhythms or other symptoms you may have
  • A Pacemaker – to control your heart rate
  • An ICD – if you are at risk of having a life threatening abnormal heart rhythm.

How will HCM affect me?

Research has shown that, with proper treatment and follow-up, most people with the condition live a normal life.

However, because there is a very small risk of getting a life-threatening abnormal heart rhythm, a small number of people with HCM are at risk of sudden cardiac death. It’s important to discuss this risk with your doctor, who may offer medication or advise that you need to have an ICD fitted if you are at an increased risk.

You may have to make some small changes to your lifestyle, such as avoiding competitive sports, but you should be able to continue to work and drive a car for example

However, you will not be able to drive an HGV or commercial passenger vehicle and you may have to reconsider manual jobs which involve strenuous activity.

Your donations help support the work of scientists like BHF Professor Hugh Watkins, who has led the way in finding the genetic mutations that cause HCM, meaning that more people with the condition can be screened and diagnosed.

For more information

Call our BHF Genetic Information Service on 0300 456 8383 to speak to one of our specialist nurses for information about inherited heart conditions and how they can affect you and your family.

For more information and advice about living with hypertrophic cardiomyopathy, download or order our booklet.