Target validation definition

Applicants should have experimental data that validates the target, often described as the 'killer experiment'.

Points to consider:

  • Do you have a target, pathway and the ability to modulate these?
  • Do you have any evidence that your target is clinically relevant e.g. evidence from GWAS studies or evidence of mutations that cause a human phenotype?
  • Have potential toxicity issues been considered?

If you are unsure whether your research is at this stage or if you require funding to get to this stage, please contact a member of the team to discuss at [email protected].