We have announced funding of over £220,000 to University of Glasgow researchers who are looking into ways to combat the causes of heart attacks and strokes.
The funding is announced as part of our new research strategy. We are committed to spending over half a billion pounds on research over the next five years.
This month in Scotland, 575 people will die from a heart attack and 1,250 people will lose their lives to cardiovascular disease.
Research in Glasgow
Dr Stephen Yarwood and his team at the University of Glasgow are looking at the type of chronic inflammation associated with heart attacks and stroke.
Dr Yarwood says: “There is an urgent need to develop new therapeutic strategies to combat the chronic inflammation associated with cardiovascular diseases.
“Chronic inflammation can develop due to increased levels of inflammatory ‘messengers’, or cytokines, in the circulation. In the case of conditions like coronary heart disease, this inflammation involves excessive ‘leakiness’ and increased attachment of white blood cells to the vascular endothelial cells or VECs that line the blood vessels.
“This causes long-term damage, including blocked arteries and blood clots, which can lead to heart attacks or strokes. Moreover, attempts to use stents to restore blocked arteries often fail due to this kind of inflammation.
“We have discovered that activation of the enzyme, EPAC1, can suppress this inflammatory activity in VECs and may therefore be an attractive therapeutic target.”
We’re currently funding over £18 million worth of cardiovascular disease research at the University of Glasgow – and nearly £58 million at universities and institutions throughout Scotland.
Help us beat heart disease in Scotland
We are totally reliant on the generosity of people who donate time and money to our cause.
This new Research Strategy means we need to raise more than half a billion pounds between now and 2020. This will be a challenge, but one we will meet head on in our fight for every heartbeat.
Please donate to help us continue funding life saving research.