Why do I need a different drug instead of aspirin?

Anticoagulants and atrial fibrillation

I’m a 75-year-old woman and I’ve had AF for 10 years. I’ve been taking aspirin for stroke prevention since my diagnosis, but my GP has recently told me that I’ll need to swap to warfarin or one of the new anticoagulants. Why have things changed?

Professor Peter Weissberg says:

Atrial fibrillation (AF) is the most common heart rhythm disturbance and is the leading cause of stroke. New guidelines have been released to help manage AF better and prevent more strokes. The revised guidance, issued by the Government’s National Institute for Health and Care Excellence, now recommends that people with AF who are at significant risk of stroke are prescribed an anticoagulant such as warfarin, dabigatran etexilate, pixaban or rivaroxaban instead of aspirin to reduce their risk.

This is due to the growing body of evidence that warfarin and the newer anticoagulants are much more effective at preventing stroke than aspirin.

However, not all people with AF need to take an anticoagulant and each person should have their risk of both stroke and bleeding assessed. This will allow your doctor to make a decision on whether an anticoagulant is appropriate.

Learn more about the new anticoagulants, such as dabigatran etexilate, apixaban or rivaroxaban

Professor Peter WeissbergMeet the expert

Professor Peter Weissberg is BHF Medical Director and Honorary Consultant Cardiologist to Addenbrooke’s Hospital. He has a special interest in atherosclerosis.

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