About the grant
In support of its mission, the GCRFF is proud to launch the International Research Challenge (IRC) on Women’s Cardiovascular Health. This first of its kind network grant aims to fund the best science in the world and to support transformative research in women’s cardiovascular health, focusing on one or more areas that represent an unmet medical need of global relevance. Please read further on for all applicant information.
Programme objectives
The 4 programme objectives of the IRC are as follows:
- address urgent knowledge gaps in women’s cardiovascular health that are of global relevance
- drive transformational change in care, clinical practice, policies and/or health outcomes for women, with international applicability
- catalyze innovation and international collaboration in women’s cardiovascular health research
- build and strengthen research capacity in women’s cardiovascular health on the international stage.
Grant structure
This funding opportunity is structured as an international, multi-institutional and multi-disciplinary research network grant. It will bring together experts from around the world to collaboratively execute a research programme delivering impacts that no single institution, country or continent could achieve on its own.
We are inviting research proposals focused on women’s cardiovascular health in areas that are under-researched and/or that require greater understanding. Relevant research areas of interest include, but are not limited to, the following areas:
- risk factors and prevention of cardiovascular disease across women’s life stages
- clinical diagnosis and treatment of conditions more prevalent or with worse outcomes among women
- sex-specific underlying mechanisms of cardiovascular disease in women.
Please see the full programme description for additional information on eligibility criteria, governance expectations and conditions of funding etc.
Grant value
One (1) grant will be awarded to the highest ranked international research network application. The total award will be a maximum of
$10 million USD over 5 years. This award is non-renewable.
Application process
This funding opportunity is a two-staged process including a Letter of Intent (LOI) and Full Application.
- LOI: open to all applicants and are due by 15 January 2025 (5pm BST)
- full application: by invitation only.
Please see the full programme description for additional information on application instructions.
To submit a LOI, please apply now to access the Fluxx portal.
Essential resources
- Download the IRC programme description
- Download the IRC privacy notice
- Webinar Questions and Answers document
- Frequently Asked Questions - Budget and Finances
Informational webinars and Q&A
Get in touch
For more information on the International Research Challenge on Women’s Cardiovascular Health, please contact [email protected]
For any other queries regarding the GCRFF, please get in touch with Global Networks Manager, Zoe Jackson at [email protected]
Partner organisations

- American Heart Association
- British Heart Foundation
- Canadian Institutes of Health Research – Institute of Circulatory and Respiratory Health
- Danish Heart Foundation (Hjerteforeningen)
- Dutch Heart Foundation (Hartstichting)
- German Centre for Cardiovascular Research (Deutsches Zentrum für Herz-Kreislauf-Forschung or DZHK)
- Heart and Stroke Foundation of Canada
- Leducq Foundation
- National Heart Foundation of Australia
- National Heart Foundation of New Zealand
- National Heart, Lung, and Blood Institute (USA)
- Swiss Heart Foundation