A tiny solution to a big problem
Over 80,000 people die each year from coronary heart
disease (CHD) and a big contributing factor is high cholesterol.
Researchers in Surrey are using nanotechnology to come up with a
way to reduce cholesterol and people’s risk of CHD and
CHD occurs when
the coronary arteries become narrowed by a gradual build-up of
fatty material in their walls – high levels of harmful LDL cholesterol in the blood contribute to this.
Many people, thanks in part to BHF-funded research, now take the
cholesterol-lowering drugs statins. But
these drugs are not suitable for all heart patients so we’re
funding research like this into alternative treatments.
How your donations help
Scientists at the University of Surrey,
working in collaboration with the University of Bath, are
developing synthetic particles that act like tiny
cleaners sweeping up the harmful cholesterol from the
bloodstream and getting rid of it through the liver. These
particles, called Polycelles, are less than a hair’s width
Thanks to your support we’re funding a
£300,000 research project into this technology. Over three years
the researchers will design and build their Polycelles before
carefully measuring and analysing them to make sure they’re
safe and effective. The team comes from a variety of
scientific disciplines and includes an expert in metabolic diseases
who will make sure the technology is designed so that it can become
a treatment for patients as soon as possible.